Characterization of bovine viral diarrhea virus isolated from cattle with hemorrhagic syndrome

Abstract

The Bovine Viral Diarrhea (BVDV) virus causes numerous pathologies that range from reproductive losses to infections of little clinical significance in the bovine digestive tract. Variation have been reported among the strains of the BVDV, which are classified into two biotypes; cytopathogenic (CP) and non-cytopathogenic (NCP), and the viral types I and II. This work describes the pathological findings in a calf with diarrhea and severe thrombocytopenia. The strain isolated (334/3) was molecularly characterized by sequencing of the 5’non-coding region (5’ NCR). These analyses revealed 90-98% homologies with reference strains type I strains and the changes associated with BVDV type II, were not found.