Normal biochemical-endocrine values helpful in controlling growth and development in German Sheepdog, Doberman and Great Dane

Abstract

To control the process of growth, the factors that intervene in it and the parameters useful to evaluate these factors must be taken into account. Information about the normal biochemical-endocrine values according to age, breed and sex, is scarce in veterinary medicine . 800 normal puppies (350 german sheepdogs, 270 dobermans and 180 great danes) from Buenos Aires city and surroundings, divided according to age, sex and breed were evaluated. The age of the puppies ranged between 30 days and 8 months (after this age, growth was not considered significant). Ca, inorganic phosphorus (Pi), total protein (Tot. Prot.), albumine, creatinine phosphokinase (CPK), serum alkaline phosphatase (SAP) and Mg were determined. Triiodotironine (T3) , tiroxine (T4) and free tiroxine (FT4) were evaluated by the radio immune assay method. Statistical methods used were: percentiles 3, 50 and 97, one way ANOVA, Tukey and Bonferroni tests. There were no significant differences (p > 0.05) due to breed and sex. Significant differences (p < 0.05) according to age were found only for: SAP, Pi, Tot. Prot., CPK and T4. The Ca, Mg, albumine, T3 and FT4 did not present significant differences according to age (p > 0.05). It was concluded that normal biochemical and endocrine values will help in the prophylaxis, precocious and accurate diagnosis of the etiology that affects growth.